Dr Jonathan Lee, together with a team of clinicians from National University Hospital (NUH), Duke-NUS, Singapore General Hospital (SGH), National University Cancer Institute, Singapore (NCIS), and the National Cancer Centre Singapore (NCCS), has secured $25 million in funding from the National Medical Research Council (NMRC) for a five-year research programme. The team aims to develop AI-driven tools for the prevention, early detection, and treatment of gastric cancer.
We are pleased to share our latest research publication in Cell Reports Medicine, led by Dr Siyan Zhao, with A/Prof Jonathan Lee and A/Prof Charlene Goh as corresponding authors.Our study reveals an important association between oral microbial nitrate metabolism and metabolic health. By analysing tongue microbiome samples from 472 participants, we identified Rothia mucilaginosa, a beneficial nitrate-reducing bacterium, as being associated with a lower prevalence of prediabetes.
Our research aims to advance understanding of the gut microbiome by employing cutting-edge techniques to analyze and characterize microbial communities and their impact on health.
We leverage artificial intelligence to enhance endoscopic imaging and diagnostics, enabling more accurate detection and characterization of gastrointestinal diseases.
Our work explores the therapeutic potential and mechanisms of fecal microbiota transplantation to restore gut microbial balance and treat gastrointestinal disorders.
The Gut–Brain Core, led by Adjunct Associate Professor Kewin Siah, is advancing research into disorders of gut–brain interaction (DGBI) with a focus on Asia-relevant evidence and therapies..
